![What Are the Potential Sites of Protein Arylation by N-Acetyl-p-benzoquinone Imine (NAPQI)? | Chemical Research in Toxicology What Are the Potential Sites of Protein Arylation by N-Acetyl-p-benzoquinone Imine (NAPQI)? | Chemical Research in Toxicology](https://pubs.acs.org/cms/10.1021/acs.chemrestox.5b00373/asset/images/large/tx-2015-00373z_0008.jpeg)
What Are the Potential Sites of Protein Arylation by N-Acetyl-p-benzoquinone Imine (NAPQI)? | Chemical Research in Toxicology
![Acetaminophen metabolism. NAPQI, N-acetyl-p-benzoquinone imine; CYP450,... | Download Scientific Diagram Acetaminophen metabolism. NAPQI, N-acetyl-p-benzoquinone imine; CYP450,... | Download Scientific Diagram](https://www.researchgate.net/publication/270016486/figure/fig1/AS:669948745613316@1536739636522/Acetaminophen-metabolism-NAPQI-N-acetyl-p-benzoquinone-imine-CYP450-cytochrome-P450.png)
Acetaminophen metabolism. NAPQI, N-acetyl-p-benzoquinone imine; CYP450,... | Download Scientific Diagram
![Acetaminophen (Paracetamol) Metabolites Induce Vasodilation and Hypotension by Activating Kv7 Potassium Channels Directly and Indirectly | Arteriosclerosis, Thrombosis, and Vascular Biology Acetaminophen (Paracetamol) Metabolites Induce Vasodilation and Hypotension by Activating Kv7 Potassium Channels Directly and Indirectly | Arteriosclerosis, Thrombosis, and Vascular Biology](https://www.ahajournals.org/cms/asset/d939ee6e-f70d-44c2-8161-24435c539442/atvbaha.120.313997.fig08.jpg)
Acetaminophen (Paracetamol) Metabolites Induce Vasodilation and Hypotension by Activating Kv7 Potassium Channels Directly and Indirectly | Arteriosclerosis, Thrombosis, and Vascular Biology
![In-source formation of N-acetyl-p-benzoquinone imine (NAPQI), the putatively toxic acetaminophen (paracetamol) metabolite, after derivatization with pentafluorobenzyl bromide and GC–ECNICI-MS analysis - ScienceDirect In-source formation of N-acetyl-p-benzoquinone imine (NAPQI), the putatively toxic acetaminophen (paracetamol) metabolite, after derivatization with pentafluorobenzyl bromide and GC–ECNICI-MS analysis - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S1570023211000596-gr1.jpg)
In-source formation of N-acetyl-p-benzoquinone imine (NAPQI), the putatively toxic acetaminophen (paracetamol) metabolite, after derivatization with pentafluorobenzyl bromide and GC–ECNICI-MS analysis - ScienceDirect
![Trapping of NAPQI, the intermediate toxic paracetamol metabolite, by aqueous sulfide (S2−) and analysis by GC–MS/MS - ScienceDirect Trapping of NAPQI, the intermediate toxic paracetamol metabolite, by aqueous sulfide (S2−) and analysis by GC–MS/MS - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S1570023214003651-sc1.jpg)
Trapping of NAPQI, the intermediate toxic paracetamol metabolite, by aqueous sulfide (S2−) and analysis by GC–MS/MS - ScienceDirect
![An Example of a Drug That Causes Toxicity Through the Formation of a Chemically Reactive Intermediate - Mechanisms of Adverse Drug Reactions | Pharmacovigilance An Example of a Drug That Causes Toxicity Through the Formation of a Chemically Reactive Intermediate - Mechanisms of Adverse Drug Reactions | Pharmacovigilance](https://www.pharmacy180.com/media/imgph04/TVdOmGw.jpg)
An Example of a Drug That Causes Toxicity Through the Formation of a Chemically Reactive Intermediate - Mechanisms of Adverse Drug Reactions | Pharmacovigilance
![University of Iowa Pathology on X: "GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. ❓How does ethanol interfere with acetaminophen metabolism? University of Iowa Pathology on X: "GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. ❓How does ethanol interfere with acetaminophen metabolism?](https://pbs.twimg.com/media/FQOuzIgXMAU6rft.png)
University of Iowa Pathology on X: "GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. ❓How does ethanol interfere with acetaminophen metabolism?
![Exposure to acetaminophen and all its metabolites upon 10, 15, and 20 mg/kg intravenous acetaminophen in very-preterm infants | Pediatric Research Exposure to acetaminophen and all its metabolites upon 10, 15, and 20 mg/kg intravenous acetaminophen in very-preterm infants | Pediatric Research](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fpr.2017.129/MediaObjects/41390_2017_Article_BFpr2017129_Fig1_HTML.jpg)
Exposure to acetaminophen and all its metabolites upon 10, 15, and 20 mg/kg intravenous acetaminophen in very-preterm infants | Pediatric Research
![Paracetamol hepatotoxicity at therapeutic doses - Vitols - 2003 - Journal of Internal Medicine - Wiley Online Library Paracetamol hepatotoxicity at therapeutic doses - Vitols - 2003 - Journal of Internal Medicine - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/9ca93579-1aa8-4f26-a255-43cfb08cf260/joim_1107_f1.gif)
Paracetamol hepatotoxicity at therapeutic doses - Vitols - 2003 - Journal of Internal Medicine - Wiley Online Library
![N-acetyl-p-benzoquinonimine metabolite as a factor of possible neurotoxicity of paracetamol - Vlasova - HERALD of North-Western State Medical University named after I.I. Mechnikov N-acetyl-p-benzoquinonimine metabolite as a factor of possible neurotoxicity of paracetamol - Vlasova - HERALD of North-Western State Medical University named after I.I. Mechnikov](https://journals.eco-vector.com/files/journals/20/articles/99620/supp/99620-215841-1-SP.jpg)